Overview
My research focuses on the biology of squamous carcinomas, a group of diseases with similar genetic origin and, conceivably, similar vulnerabilities. I am particularly interested in identifying the origins of the heterogeneity that is so prominent in lung squamous cell carcinomas (LUSC), modelling and investigating precancerous stages and identifying vulnerabilities associated to the different LUSC subtypes.
In addition, I have a special interest in developing human models of cancer to reduce the number of animals in research. To do that, we use human cells and organoids to model squamous carcinomas.
Qualifications
- PhD: Involvement of polyamine metabolism in mouse pregnancy
University of Murcia, 2002–2007 - BSc: Pharmacy
University of Valencia, 1995–1998
Postgraduate Project Opportunities
I am willing to supervise a PhD
Publications
2025
- Published
Ogden, J., Sellers, R., Sahoo, S., Oojageer, A., Chaturvedi, A., Dive, C. & Lopez-Garcia, C., 4 Apr 2025, In: Nature Communications. 16, 1, p. 3215
Research output: Contribution to journal › Article › peer-review
2023
- Published
Roberts, M., Ogden, J., Hossain, A. S. M., Chaturvedi, A., Kerr, A. R. W., Dive, C., Beane, J. E. & Lopez-Garcia, C., 24 Mar 2023, In: Elife. 12
Research output: Contribution to journal › Article › peer-review
2022
- Published
Lambertos, A., Nuñez-Sanchez, M. A., López-GarcÃa, C., López-Contreras, A. J., Ramos-Molina, B. & Peñafiel, R., 21 Dec 2022, In: Biomolecules. 13, 1
Research output: Contribution to journal › Article › peer-review - Published
Mumby, S., Kermani, N. Z., Garnett, J. P., Pavlidis, S., Wilson, S. J., Howarth, P. J., Thomas, M. J., Adcock, I. M. & López-GarcÃa, C., 1 Nov 2022, In: Allergy. 77, 11, p. 3463-3466 4 p.
Research output: Contribution to journal › Article › peer-review
2018
- Published
Gronroos, E. & López-GarcÃa, C., 1 Dec 2018, In: Cancer Research. 78, 23, p. 6529-6535 7 p.
Research output: Contribution to journal › Review article › peer-review
2017
- Published
Sansregret, L., Patterson, J. O., Dewhurst, S., López-GarcÃa, C., Koch, A., McGranahan, N., Chao, W. C. H., Barry, D. J., Rowan, A., Instrell, R., Horswell, S., Way, M., Howell, M., Singleton, M. R., Medema, R. H., Nurse, P., Petronczki, M. & Swanton, C., 5 Feb 2017, In: Cancer discovery. 7, 2, p. 218-233 16 p.
Research output: Contribution to journal › Article › peer-review - Published
López-GarcÃa, C., Sansregret, L., Domingo, E., McGranahan, N., Hobor, S., Birkbak, N. J., Horswell, S., Grönroos, E., Favero, F., Rowan, A. J., Matthews, N., Begum, S., Phillimore, B., Burrell, R., Oukrif, D., Spencer-Dene, B., Kovac, M., Stamp, G., Stewart, A. & Danielsen, H. & 3 others, Novelli, M., Tomlinson, I. & Swanton, C., 9 Jan 2017, In: Cancer cell. 31, 1, p. 79-93 15 p.
Research output: Contribution to journal › Article › peer-review
2016
- Published
Cremades, A., Del Rio-Garcia, J., Lambertos, A., López-Garcia, C. & Peñafiel, R., 13 May 2016, In: SpringerPlus. 5, p. 616
Research output: Contribution to journal › Article › peer-review
2013
- Published
López-Garcia, C., Ramos-Molina, B., Lambertos, A., López-Contreras, A. J., Cremades, A. & Peñafiel, R., 12 Jul 2013, In: PLoS ONE. 8, 7, p. e69188
Research output: Contribution to journal › Article › peer-review
2010
- Published
Lopez-Garcia, C., Klein, A. M., Simons, B. D. & Winton, D. J., 5 Nov 2010, In: Science. 330, 6005, p. 822-5 4 p.
Research output: Contribution to journal › Article › peer-review
2009
- Published
Lopez-Garcia, C., Lopez-Contreras, A. J., Cremades, A., Castells, M. T. & Peñafiel, R., 1 Mar 2009, In: Placenta. 30, 3, p. 241-9 9 p.
Research output: Contribution to journal › Article › peer-review
2008
- Published
López-GarcÃa, C., López-Contreras, A. J., Cremades, A., Castells, M. T., MarÃn, F., Schreiber, F. & Peñafiel, R., Oct 2008, In: Endocrinology. 149, 10, p. 5012-23 12 p.
Research output: Contribution to journal › Article › peer-review - Published
López-Contreras, A. J., Galindo, J. D., López-GarcÃa, C., Castells, M. T., Cremades, A. & Peñafiel, R., 1 Mar 2008, In: Journal of Endocrinology. 196, 3, p. 615-24 10 p.
Research output: Contribution to journal › Article › peer-review
2007
- Published
Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-GarcÃa, C., Sánchez-Mas, J. & Peñafiel, R., 1 Apr 2007, In: American journal of physiology. Endocrinology and metabolism. 292, 4, p. E1010-7
Research output: Contribution to journal › Article › peer-review
2006
- Published
López-Contreras, A. J., López-Garcia, C., Jiménez-Cervantes, C., Cremades, A. & Peñafiel, R., 13 Oct 2006, In: Journal of Biological Chemistry. 281, 41, p. 30896-906 11 p.
Research output: Contribution to journal › Article › peer-review
2005
- Published
Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-GarcÃa, C., Tejada, F. & Peñafiel, R., 1 Feb 2005, In: Endocrinology. 146, 2, p. 666-74 9 p.
Research output: Contribution to journal › Article › peer-review