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Dr Carlos Lopez-Garcia

Lecturer

c.lopezgarcia@bangor.ac.uk

Overview

My research focuses on the biology of squamous carcinomas, a group of diseases with similar genetic origin and, conceivably, similar vulnerabilities. I am particularly interested in identifying the origins of the heterogeneity that is so prominent in lung squamous cell carcinomas (LUSC), modelling and investigating precancerous stages and identifying vulnerabilities associated to the different LUSC subtypes.

In addition, I have a special interest in developing human models of cancer to reduce the number of animals in research. To do that, we use human cells and organoids to model squamous carcinomas.

Qualifications

  • PhD: Involvement of polyamine metabolism in mouse pregnancy
    University of Murcia, 2002–2007
  • BSc: Pharmacy
    University of Valencia, 1995–1998

Postgraduate Project Opportunities

I am willing to supervise a PhD

Publications

2025

  • Published
    Ogden, J., Sellers, R., Sahoo, S., Oojageer, A., Chaturvedi, A., Dive, C. & Lopez-Garcia, C., 4 Apr 2025, In: Nature Communications. 16, 1, p. 3215
    Research output: Contribution to journal › Article › peer-review

2023

  • Published
    Roberts, M., Ogden, J., Hossain, A. S. M., Chaturvedi, A., Kerr, A. R. W., Dive, C., Beane, J. E. & Lopez-Garcia, C., 24 Mar 2023, In: Elife. 12
    Research output: Contribution to journal › Article › peer-review

2022

  • Published
    Lambertos, A., Nuñez-Sanchez, M. A., López-García, C., López-Contreras, A. J., Ramos-Molina, B. & Peñafiel, R., 21 Dec 2022, In: Biomolecules. 13, 1
    Research output: Contribution to journal › Article › peer-review
  • Published
    Mumby, S., Kermani, N. Z., Garnett, J. P., Pavlidis, S., Wilson, S. J., Howarth, P. J., Thomas, M. J., Adcock, I. M. & López-García, C., 1 Nov 2022, In: Allergy. 77, 11, p. 3463-3466 4 p.
    Research output: Contribution to journal › Article › peer-review

2018

  • Published
    Gronroos, E. & López-García, C., 1 Dec 2018, In: Cancer Research. 78, 23, p. 6529-6535 7 p.
    Research output: Contribution to journal › Review article › peer-review

2017

  • Published
    Sansregret, L., Patterson, J. O., Dewhurst, S., López-García, C., Koch, A., McGranahan, N., Chao, W. C. H., Barry, D. J., Rowan, A., Instrell, R., Horswell, S., Way, M., Howell, M., Singleton, M. R., Medema, R. H., Nurse, P., Petronczki, M. & Swanton, C., 5 Feb 2017, In: Cancer discovery. 7, 2, p. 218-233 16 p.
    Research output: Contribution to journal › Article › peer-review
  • Published
    López-García, C., Sansregret, L., Domingo, E., McGranahan, N., Hobor, S., Birkbak, N. J., Horswell, S., Grönroos, E., Favero, F., Rowan, A. J., Matthews, N., Begum, S., Phillimore, B., Burrell, R., Oukrif, D., Spencer-Dene, B., Kovac, M., Stamp, G., Stewart, A. & Danielsen, H. & 3 others, Novelli, M., Tomlinson, I. & Swanton, C., 9 Jan 2017, In: Cancer cell. 31, 1, p. 79-93 15 p.
    Research output: Contribution to journal › Article › peer-review

2016

  • Published
    Cremades, A., Del Rio-Garcia, J., Lambertos, A., López-Garcia, C. & Peñafiel, R., 13 May 2016, In: SpringerPlus. 5, p. 616
    Research output: Contribution to journal › Article › peer-review

2013

  • Published
    López-Garcia, C., Ramos-Molina, B., Lambertos, A., López-Contreras, A. J., Cremades, A. & Peñafiel, R., 12 Jul 2013, In: PLoS ONE. 8, 7, p. e69188
    Research output: Contribution to journal › Article › peer-review

2010

  • Published
    Lopez-Garcia, C., Klein, A. M., Simons, B. D. & Winton, D. J., 5 Nov 2010, In: Science. 330, 6005, p. 822-5 4 p.
    Research output: Contribution to journal › Article › peer-review

2009

  • Published
    Lopez-Garcia, C., Lopez-Contreras, A. J., Cremades, A., Castells, M. T. & Peñafiel, R., 1 Mar 2009, In: Placenta. 30, 3, p. 241-9 9 p.
    Research output: Contribution to journal › Article › peer-review

2008

  • Published
    López-García, C., López-Contreras, A. J., Cremades, A., Castells, M. T., Marín, F., Schreiber, F. & Peñafiel, R., Oct 2008, In: Endocrinology. 149, 10, p. 5012-23 12 p.
    Research output: Contribution to journal › Article › peer-review
  • Published
    López-Contreras, A. J., Galindo, J. D., López-García, C., Castells, M. T., Cremades, A. & Peñafiel, R., 1 Mar 2008, In: Journal of Endocrinology. 196, 3, p. 615-24 10 p.
    Research output: Contribution to journal › Article › peer-review

2007

  • Published
    Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-García, C., Sánchez-Mas, J. & Peñafiel, R., 1 Apr 2007, In: American journal of physiology. Endocrinology and metabolism. 292, 4, p. E1010-7
    Research output: Contribution to journal › Article › peer-review

2006

  • Published
    López-Contreras, A. J., López-Garcia, C., Jiménez-Cervantes, C., Cremades, A. & Peñafiel, R., 13 Oct 2006, In: Journal of Biological Chemistry. 281, 41, p. 30896-906 11 p.
    Research output: Contribution to journal › Article › peer-review

2005

  • Published
    Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-García, C., Tejada, F. & Peñafiel, R., 1 Feb 2005, In: Endocrinology. 146, 2, p. 666-74 9 p.
    Research output: Contribution to journal › Article › peer-review

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